Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 2/20 | 0.36 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333277 | 0.85 | LAP3 (0.42) | LAP3PIN1ANPEPPOLBACP3 | |
| SCHEMBL7340346 | 0.74 | LAP3 (0.42) | LAP3PIN1ANPEPACP3 | |
| SCHEMBL7321502 | 0.74 | TSHR (0.41) | GAAPOLBKDM4EALDH1A1LMNA | |
| SCHEMBL10714489 | 0.73 | LAP3 (0.51) | LAP3PIN1ANPEPPOLBACP3 | |
| SCHEMBL10359471 | 0.73 | TAAR1 (0.42) | — | |
| SCHEMBL14190589 | 0.72 | GAA (0.41) | GAAPOLBKDM4EALDH1A1LMNA | |
| SCHEMBL18952195 | 0.71 | POLB (0.45) | LAP3GAAPIN1POLBKDM4E | |
| SCHEMBL6938225 | 0.71 | CPA1 (0.41) | LAP3 | |
| SCHEMBL7340348 | 0.71 | ANPEP (0.43) | ANPEPACP3TSHR | |
| SCHEMBL12876206 | 0.71 | LAP3 (0.49) | LAP3GAAPIN1ANPEPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916679-B1 | Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-5952327-A | NEUTRAL ENDOPEPTIDASE INHIBITORS; TREATMENT OF CARDIOVASCULAR DISORDERS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1999-09-14 | — | — | US | disclosed |
| EP-0916679-A1 | Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds | Solvay Pharmaceuticals GmbH (DE) | 1999-05-19 | — | — | EP | disclosed |