Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378197 | 0.77 | FDPS (0.43) | S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL7425913 | 0.71 | PPARG (0.50) | — | |
| SCHEMBL6515182 | 0.71 | PPARG (0.50) | — | |
| SCHEMBL7333277 | 0.71 | LAP3 (0.42) | ANPEPACP3 | |
| SCHEMBL7340343 | 0.71 | LAP3 (0.42) | ANPEPACP3TSHR | |
| SCHEMBL8916211 | 0.71 | ANPEP (0.58) | ANPEPERAP1ERAP2S1PR2S1PR4 | |
| SCHEMBL7340346 | 0.70 | LAP3 (0.42) | ANPEPACP3 | |
| SCHEMBL8621508 | 0.70 | FDFT1 (0.49) | ANPEPERAP1ERAP2S1PR2S1PR4 | |
| SCHEMBL7605703 | 0.70 | ANPEP (0.56) | ANPEPERAP1ERAP2S1PR2S1PR4 | |
| SCHEMBL27430208 | 0.69 | S1PR2 (0.55) | ANPEPERAP1ERAP2S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952327-A | NEUTRAL ENDOPEPTIDASE INHIBITORS; TREATMENT OF CARDIOVASCULAR DISORDERS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1999-09-14 | — | — | US | disclosed |