Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 5/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333277 | 0.79 | LAP3 (0.42) | LAP3ANPEPACP3TRPA1MEN1 | |
| SCHEMBL10359471 | 0.78 | TAAR1 (0.42) | TRPA1CYP2D6MEN1KMT2ACTRB1 | |
| SCHEMBL7340343 | 0.74 | LAP3 (0.42) | LAP3ANPEPACP3PIN1 | |
| SCHEMBL6938225 | 0.73 | CPA1 (0.41) | LAP3MEN1KMT2ACTRB1CYP1A2 | |
| SCHEMBL27652200 | 0.71 | BLM (0.40) | MEN1KMT2ACTRB1CYP1A2 | |
| SCHEMBL7307715 | 0.71 | SRR (0.56) | — | |
| SCHEMBL7321720 | 0.71 | SRR (0.56) | — | |
| SCHEMBL7307706 | 0.71 | SRR (0.56) | — | |
| SCHEMBL7340348 | 0.70 | ANPEP (0.43) | ANPEPACP3 | |
| SCHEMBL2943750 | 0.69 | MEN1 (0.51) | MEN1KMT2ACTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952327-A | NEUTRAL ENDOPEPTIDASE INHIBITORS; TREATMENT OF CARDIOVASCULAR DISORDERS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1999-09-14 | — | — | US | disclosed |