Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340548 | 1.00 | FAAH (0.54) | FAAHSOAT1CYP1A2CYP2C19MEN1 | |
| SCHEMBL31215306 | 0.87 | SOAT1 (0.44) | FAAHSOAT1CYP1A2CYP2C19MEN1 | |
| SCHEMBL7340545 | 0.84 | TSHR (0.48) | FAAHSOAT1CYP1A2CYP2C19MEN1 | |
| Urea SCHEMBL29070646 | 0.79 | FAAH (0.70) | FAAHSOAT1CYP1A2CYP2C19MEN1 | |
| SCHEMBL20654552 | 0.76 | FFAR1 (0.40) | FAAHSOAT1CYP1A2CYP2C19MEN1 | |
| SCHEMBL20835136 | 0.75 | PPARG (0.49) | FAAHCYP1A2CYP2C19CYP3A4KMT2A | |
| SCHEMBL7345972 | 0.75 | FAAH (0.40) | FAAHSOAT1CYP1A2CYP2C19MEN1 | |
| SCHEMBL9407900 | 0.75 | FAAH (0.56) | FAAHSOAT1CYP1A2CYP2C19MEN1 | |
| SCHEMBL7345976 | 0.75 | FAAH (0.40) | FAAHSOAT1CYP1A2CYP2C19MEN1 | |
| SCHEMBL31298580 | 0.73 | FAAH (0.79) | FAAHSOAT1CYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639468-A | Derivatives of glycinamide, their preparation and their use | CONTINENTAL PHARMA INC. (BE) | 1987-01-27 | — | — | US | disclosed |