Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345976 | 1.00 | FAAH (0.40) | FAAHSOAT1ALDH1A1MAPTMEN1 | |
| SCHEMBL18945544 | 0.80 | CNR2 (0.34) | SOAT1ALDH1A1CNR1KCNK3THRB | |
| SCHEMBL7345987 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP3A4 | |
| SCHEMBL7340540 | 0.75 | FAAH (0.54) | FAAHSOAT1MAPTMEN1TP53 | |
| SCHEMBL7340548 | 0.75 | FAAH (0.54) | FAAHSOAT1MAPTMEN1TP53 | |
| SCHEMBL27998395 | 0.74 | PPARG (0.36) | FAAHALDH1A1CNR1KCNK3THRB | |
| SCHEMBL3901539 | 0.73 | FAAH (0.65) | FAAHSOAT1MAPTMEN1TP53 | |
| SCHEMBL3901535 | 0.73 | FAAH (0.65) | FAAHSOAT1MAPTMEN1TP53 | |
| SCHEMBL29277561 | 0.73 | CNR1 (0.39) | FAAHSOAT1ALDH1A1MAPTMEN1 | |
| SCHEMBL7348552 | 0.72 | ALDH1A1 (0.40) | ALDH1A1CYP3A4KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639468-A | Derivatives of glycinamide, their preparation and their use | CONTINENTAL PHARMA INC. (BE) | 1987-01-27 | — | — | US | disclosed |