Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215306 | 0.89 | SOAT1 (0.44) | SOAT1CYP3A4MEN1FAAHTP53 | |
| SCHEMBL11438610 | 0.86 | TSHR (0.50) | TSHRFAAHCYP1A2CYP2C19PLA2G2C | |
| SCHEMBL7340548 | 0.84 | FAAH (0.54) | SOAT1CYP3A4MEN1FAAHTP53 | |
| SCHEMBL7340540 | 0.84 | FAAH (0.54) | SOAT1CYP3A4MEN1FAAHTP53 | |
| SCHEMBL25340146 | 0.79 | TSHR (0.57) | TSHRPLA2G2CKDM4EALDH1A1 | |
| Urea SCHEMBL9615746 | 0.78 | TSHR (0.73) | TSHRSOAT1CYP3A4MEN1FAAH | |
| Urea SCHEMBL9070468 | 0.78 | TSHR (0.73) | TSHRSOAT1CYP3A4MEN1FAAH | |
| Urea SCHEMBL17003979 | 0.78 | TSHR (0.73) | TSHRSOAT1CYP3A4MEN1FAAH | |
| Urea SCHEMBL8671912 | 0.78 | TSHR (0.73) | TSHRSOAT1CYP3A4MEN1FAAH | |
| SCHEMBL7345987 | 0.78 | ALDH1A1 (0.41) | TSHRCYP3A4ALDH1A1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639468-A | Derivatives of glycinamide, their preparation and their use | CONTINENTAL PHARMA INC. (BE) | 1987-01-27 | — | — | US | disclosed |