Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313464 | 0.88 | MMEL1 (0.49) | MMEMMEL1CTSLCTSS | |
| SCHEMBL7308199 | 0.87 | MMEL1 (0.50) | MMEMMEL1CTSLCTSS | |
| SCHEMBL489231 | 0.87 | MMEL1 (0.64) | MMEMMEL1ACE | |
| SCHEMBL489232 | 0.87 | MMEL1 (0.64) | MMEMMEL1ACE | |
| SCHEMBL7417467 | 0.86 | MME (0.53) | MMEACE | |
| SCHEMBL7417475 | 0.86 | MME (0.53) | MMEACE | |
| Bromide SCHEMBL9683926 | 0.86 | MMEL1 (0.62) | MMEMMEL1ACE | |
| SCHEMBL9682406 | 0.84 | MMEL1 (0.54) | MMEMMEL1ACE | |
| SCHEMBL7345172 | 0.83 | MMEL1 (0.52) | MMEMMEL1 | |
| SCHEMBL7317532 | 0.83 | MMEL1 (0.52) | MMEL1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |