Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343653 | 0.90 | MMEL1 (0.44) | MMEL1MME | |
| SCHEMBL489231 | 0.87 | MMEL1 (0.64) | MMEL1MME | |
| SCHEMBL489232 | 0.87 | MMEL1 (0.64) | MMEL1MME | |
| SCHEMBL7417523 | 0.86 | ITGA4 (0.59) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7417516 | 0.86 | ITGA4 (0.59) | ITGA4ITGB1ITGB7 | |
| Bromide SCHEMBL9683926 | 0.86 | MMEL1 (0.62) | MMEL1MME | |
| SCHEMBL7340874 | 0.83 | MME (0.53) | MMEL1MME | |
| SCHEMBL7348411 | 0.82 | MMEL1 (0.45) | MMEL1MME | |
| SCHEMBL7343519 | 0.81 | MMEL1 (0.54) | MMEL1MME | |
| SCHEMBL9682406 | 0.81 | MMEL1 (0.54) | MMEL1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |