Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NMBR | P28336 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340910 | 1.00 | PSMB1 (0.42) | PSMB1PSMB5PSMB2ALDH1A1POLB | |
| SCHEMBL7303217 | 0.94 | CAPN1 (0.48) | PSMB1PSMB5PSMB2CTSLCTSK | |
| SCHEMBL7430388 | 0.94 | CAPN1 (0.48) | PSMB1PSMB5PSMB2CTSLCTSK | |
| SCHEMBL7349120 | 0.89 | CTSB (0.43) | ALDH1A1POLBCTSLCTSKMAPT | |
| SCHEMBL9185368 | 0.89 | CTSB (0.43) | ALDH1A1POLBCTSLCTSKMAPT | |
| SCHEMBL7347081 | 0.89 | TACR1 (0.49) | ALDH1A1CTSLCTSKCTSBCTSS | |
| SCHEMBL7347088 | 0.89 | TACR1 (0.49) | ALDH1A1CTSLCTSKCTSBCTSS | |
| SCHEMBL7303213 | 0.88 | PSMB1 (0.41) | PSMB1PSMB5PSMB2ALDH1A1POLB | |
| SCHEMBL7304428 | 0.86 | CAPN1 (0.57) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7312633 | 0.86 | CAPN1 (0.52) | CTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603873-B1 | Aminoketone derivatives | MITSUBISHI CHEM CORP (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5424325-A | Inibitors of thiol protease and may be used as therapeutic agents for treating muscular dystrophy, cataracts, strokes | MITSUBISHI KASEI CORPORATION (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0603873-A1 | Aminoketone derivatives | Mitsubishi Chemical Corporation (JP) | 1994-06-29 | — | — | EP | disclosed |