Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734040 | 0.89 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL19225658 | 0.74 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL734691 | 0.71 | CNR2 (0.40) | CNR2 | |
| SCHEMBL2507068 | 0.70 | HPGD (0.36) | — | |
| SCHEMBL734065 | 0.67 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL735313 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL733529 | 0.65 | HPGD (0.38) | CNR2 | |
| SCHEMBL9050766 | 0.63 | ADORA2A (0.36) | — | |
| SCHEMBL23320022 | 0.63 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL736352 | 0.61 | L3MBTL1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138187-B2 | Substituted heteroaryl derivatives | GRUENENTHAL GMBH (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20100009986-A1 | SUBSTITUTED HETEROARYL DERIVATIVES | GRUNENTHAL GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009986-A1 | SUBSTITUTED HETEROARYL DERIVATIVES | CYP3A43, HMGCR, ABCG2 | CNR2 199/4885CNR1 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.