Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | MC3R | P41968 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 8/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL7341872 | 0.85 | KMT2A (0.57) | MEN1KMT2AKDM4ELMNAMPO | |
| Dl-Tryptophan SCHEMBL7341866 | 0.85 | KMT2A (0.57) | MEN1KMT2AKDM4ELMNAMPO | |
| Phenylalanine SCHEMBL10381280 | 0.85 | KMT2A (0.70) | MEN1KMT2AKDM4ELMNAMPO | |
| SCHEMBL1239230 | 0.85 | MEN1 (0.59) | MEN1KMT2AKDM4ELMNAMPO | |
| SCHEMBL6032937 | 0.84 | KMT2A (0.71) | MEN1KMT2AKDM4ELMNAMPO | |
| SCHEMBL597229 | 0.84 | KMT2A (0.71) | MEN1KMT2AKDM4ELMNAMPO | |
| Tryptophan SCHEMBL8508161 | 0.84 | GHSR (0.46) | MEN1KMT2AKDM4ELMNAMPO | |
| Valine SCHEMBL8434539 | 0.83 | GHSR (0.43) | MEN1KMT2AKDM4ELMNAMPO | |
| Valine SCHEMBL8584754 | 0.83 | GHSR (0.43) | MEN1KMT2AKDM4ELMNAMPO | |
| Dl-Tryptophan SCHEMBL21219049 | 0.82 | KMT2A (0.71) | MEN1KMT2AKDM4ELMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084465-A2 | MODELING BIOLOGICAL SYSTEMS | SRI INTERNATIONAL, INC. (US) | 2003-10-16 | — | — | WO | disclosed |