Tryptophan

Tryptophan

SCHEMBL8508161

CC(C)[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)OC(=O)[C@@H](N)CCC(N)=O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.N[C@@H](Cc1ccc(OC(=O)[C@@H]2CCCN2)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 12/20 0.46
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
MPO P05164 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
HIF1A Q16665 1/20 0.39
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
LTA4H P09960 1/20 0.38
PLA2G2A P14555 1/20 0.38
MC4R P32245 2/20 0.38
MC5R P33032 1/20 0.38
MC3R P41968 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL5705404 0.95 GHSR (0.44) GHSRMEN1KMT2AKDM4ELMNA
Tryptophan SCHEMBL8508162 0.86 GHSR (0.48) GHSRMEN1KMT2AKDM4ELMNA
Tryptophan SCHEMBL5705407 0.84 GHSR (0.46) GHSRMEN1KMT2AKDM4ELMNA
Phenylalanine SCHEMBL7341867 0.84 MEN1 (0.50) GHSRMEN1KMT2AKDM4ELMNA
Tryptophan SCHEMBL7296886 0.81 GHSR (0.39) GHSR
Tryptophan SCHEMBL28607194 0.80 GHSR (0.48) GHSRMEN1KMT2AKDM4ELMNA
Tryptophan SCHEMBL3495872 0.79 KDM4E (0.59) GHSRMEN1KMT2AKDM4ELMNA
Tryptophan SCHEMBL9641499 0.79 GHSR (0.49) GHSRMEN1KMT2AKDM4ELMNA
Tryptophan SCHEMBL8157265 0.79 MEN1 (0.39) GHSRMEN1KMT2AKDM4ELMNA
Tryptophan SCHEMBL17181203 0.78 GHSR (0.42) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912718-A1 METHOD FOR PROTEIN STABILISATION OF WINES Societe d'Applications de Recherches et de Conseils Oenologiques (SARCO) (FR) 1999-05-06 EP disclosed
WO-1997049794-A1 METHOD FOR PROTEIN STABILISATION OF WINES SOCIETE D'APPLICATIONS DE RECHERCHES ET DE CONSEILS OENOLOGIQUES (SARCO) (FR) 1997-12-31 WO disclosed