Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344792 | 0.79 | ADRA1D (0.43) | MEN1MAPTKMT2AKDM4EUSP2 | |
| SCHEMBL3288376 | 0.79 | MAPT (0.46) | MEN1MAPTKMT2AKDM4EUSP2 | |
| SCHEMBL7343343 | 0.79 | MAPT (0.42) | MEN1MAPTKMT2AKDM4EUSP2 | |
| SCHEMBL3746625 | 0.78 | FFAR1 (0.49) | MEN1MAPTKMT2AKDM4EUSP2 | |
| SCHEMBL17378907 | 0.77 | CYP1A2 (0.39) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL27920637 | 0.77 | HDAC3 (0.40) | MAPTKDM4EALDH1A1L3MBTL1HTT | |
| SCHEMBL28104163 | 0.76 | FFAR1 (0.45) | MEN1MAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL17423629 | 0.75 | ALDH1A1 (0.39) | MEN1MAPTKMT2AKDM4EUSP2 | |
| SCHEMBL12598685 | 0.75 | FFAR1 (0.46) | MEN1MAPTKMT2AKDM4EUSP2 | |
| SCHEMBL958307 | 0.75 | IDO1 (0.54) | IDO1RXRARXRBRXRGAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5968938-A | Piperazine oxytocin receptor antagonists | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |