Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343343 | 0.83 | MAPT (0.42) | ADRA1DADRA1AADRA1BMEN1MAPT | |
| SCHEMBL3288376 | 0.83 | MAPT (0.46) | ADRA1DADRA1AADRA1BMEN1MAPT | |
| SCHEMBL24817101 | 0.81 | PTGDR2 (0.43) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL15778596 | 0.81 | KDM2B (0.45) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL7344505 | 0.81 | CXCL8 (0.44) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL17423629 | 0.79 | ALDH1A1 (0.39) | ADRA1DADRA1AADRA1BMEN1MAPT | |
| SCHEMBL7342162 | 0.79 | MEN1 (0.39) | ADRA1DADRA1AADRA1BMEN1MAPT | |
| SCHEMBL19859187 | 0.79 | L3MBTL1 (0.42) | MEN1MAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL28935348 | 0.78 | MAPT (0.47) | ADRA1DADRA1AADRA1BMEN1MAPT | |
| SCHEMBL18528840 | 0.78 | TRPV4 (0.43) | MEN1MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5968938-A | Piperazine oxytocin receptor antagonists | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |