Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.63 |
| ▸ | ACE | P12821 | 6/20 | 0.63 |
| ▸ | ECE1 | P42892 | 3/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.49 |
| ▸ | CPA1 | P15085 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311905 | 0.86 | MME (0.73) | MMEACEECE1ACE2CPA1 | |
| SCHEMBL7411123 | 0.81 | MME (0.62) | MMEACEECE1ACE2CPA1 | |
| SCHEMBL7411127 | 0.81 | MME (0.62) | MMEACEECE1ACE2CPA1 | |
| SCHEMBL7344479 | 0.80 | MME (0.61) | MMEACEECE1ACE2CPA1 | |
| SCHEMBL7342243 | 0.79 | MME (0.61) | MMEACEECE1ACE2CPA1 | |
| SCHEMBL7316768 | 0.76 | MMEL1 (0.55) | MMEACEECE1 | |
| SCHEMBL489232 | 0.75 | MMEL1 (0.64) | MMEACEECE1 | |
| SCHEMBL489231 | 0.75 | MMEL1 (0.64) | MMEACEECE1 | |
| SCHEMBL7319125 | 0.75 | MME (0.55) | MMEACEECE1 | |
| SCHEMBL43351 | 0.75 | MME (0.62) | MMEACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |