Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.61 |
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | ANPEP | P15144 | 2/20 | 0.60 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311905 | 0.88 | MME (0.73) | MMEACEECE1CPA1ACE2 | |
| SCHEMBL7411123 | 0.84 | MME (0.62) | MMEACEECE1CPA1ACE2 | |
| SCHEMBL7411127 | 0.84 | MME (0.62) | MMEACEECE1CPA1ACE2 | |
| SCHEMBL8861599 | 0.81 | MME (0.79) | MMEANPEP | |
| SCHEMBL14297648 | 0.81 | CTSS (0.60) | MMEACEANPEPCPA1ACE2 | |
| SCHEMBL10119263 | 0.81 | CTSS (0.60) | MMEACEANPEPCPA1ACE2 | |
| SCHEMBL15202503 | 0.81 | L3MBTL1 (0.63) | MMEACEECE1 | |
| SCHEMBL7319125 | 0.80 | MME (0.55) | MMEACEECE1 | |
| SCHEMBL7342243 | 0.80 | MME (0.61) | MMEACEECE1CPA1ACE2 | |
| SCHEMBL7342255 | 0.80 | MME (0.63) | MMEACEECE1CPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |