Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 3/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310571 | 0.95 | MMEL1 (0.53) | MMEL1MMEACEECE1 | |
| SCHEMBL489232 | 0.93 | MMEL1 (0.64) | MMEL1MMEACEECE1 | |
| SCHEMBL489231 | 0.93 | MMEL1 (0.64) | MMEL1MMEACEECE1 | |
| Bromide SCHEMBL9683926 | 0.92 | MMEL1 (0.62) | MMEL1MMEACEECE1 | |
| SCHEMBL7322636 | 0.87 | SRC (0.49) | MMEL1 | |
| SCHEMBL7314983 | 0.86 | MMEL1 (0.50) | MMEL1 | |
| SCHEMBL15202503 | 0.86 | L3MBTL1 (0.63) | MMEL1MMEACEECE1 | |
| SCHEMBL7319125 | 0.85 | MME (0.55) | MMEACEECE1 | |
| SCHEMBL9683662 | 0.85 | MMEL1 (0.54) | MMEL1MMEACEECE1 | |
| SCHEMBL7343519 | 0.85 | MMEL1 (0.54) | MMEL1MMEACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |