Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.78 |
| ▸ | CCND1 | P24385 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701168 | 1.00 | CDK4 (0.78) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL24398975 | 0.93 | CDK4 (0.82) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL29368287 | 0.93 | CDK4 (0.82) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL1293253 | 0.93 | CDK4 (0.82) | CDK4CCND1LMNAHTR2AHTR2C | |
| Phosphoric Acid SCHEMBL6511008 | 0.92 | CDK4 (0.66) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL30063707 | 0.88 | CDK4 (0.76) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL734246 | 0.88 | CDK4 (0.76) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL11366447 | 0.83 | CDK4 (1.00) | CDK4CCND1LMNAHTR2AHTR2C | |
| Alcohol SCHEMBL734139 | 0.83 | CDK4 (0.68) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL4863420 | 0.81 | CDK4 (0.78) | CDK4CCND1LMNAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276288-B | Synthesis method and application of chiral alpha-propargyl-3-indole compound and derivative thereof | 中山大学 | 2023-11-03 | — | — | CN | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| CN-117229264-A | Aryl Schiff base compound containing 2-aminopyrimidine structure and application thereof | 辽宁大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-114276288-B | Synthesis method and application of chiral alpha-propargyl-3-indole compound and derivative thereof | 中山大学 | 2023-11-03 | — | — | CN | disclosed |
| EP-3298003-B1 | BENZOIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2023-04-19 | — | — | EP | disclosed |
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-111825658-A | Novel EGFR (epidermal growth factor receptor) triple-mutation inhibitor and application thereof | 华东理工大学 | 2020-10-27 | — | — | CN | disclosed |
| WO-2020211853-A1 | NOVEL EGFR TRIPLE MUTATION INHIBITOR AND APPLICATION THEREOF | 华东理工大学 | 2020-10-22 | — | — | WO | disclosed |
| WO-2020211853-A1 | NOVEL EGFR TRIPLE MUTATION INHIBITOR AND APPLICATION THEREOF | 华东理工大学 | 2020-10-22 | — | — | WO | disclosed |
| US-20180030264-A1 | Benzoxazine Low Temperature Curable Composition | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC | 2018-02-01 | — | — | US | disclosed |
| CN-107428708-A | Benzoxazine low temperature cure composition | 亨斯迈先进材料美国有限责任公司 | 2017-12-01 | — | — | CN | disclosed |
| EP-0464558-A1 | Antimigraine alkoxypyrimidine derivatives | Bristol-Myers Squibb Company (US) | 1992-01-08 | — | — | EP | disclosed |
| CN-1056699-A | Latent catalysts and cure-inhibited epoxy resin compositions and laminates made therefrom | DOW CHEMICAL CO (US) | 1991-12-04 | — | — | CN | disclosed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
| WO-1979001037-A1 | 1-HYDROXYALKANAMINE PYRANO(3,4-B)INDOLE DERIVATIVES | AMERICAN HOME PROD (US) | 1979-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030264-A1 | Benzoxazine Low Temperature Curable Composition | CRYZ, PIEZO1, PSMD12 | CDK4 1654/4885CCND1 1405/4885LMNA 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.