Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344668 | 0.95 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL9204550 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL8156417 | 0.84 | L3MBTL1 (0.66) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL10051650 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL1339942 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL1098462 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ALMNAMAPT | |
| SCHEMBL10619771 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL10051646 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7335804 | 0.81 | RAB9A (0.58) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7335810 | 0.81 | RAB9A (0.58) | ALDH1A1KDM4EKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |