Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FADS1 | O60427 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720692 | 1.00 | GAA (0.54) | GAAPOLBMAPTKDM4ERAB9A | |
| SCHEMBL7377502 | 0.91 | KMT2A (0.62) | GAAPOLBMAPTKDM4ERAB9A | |
| SCHEMBL6724308 | 0.90 | LMNA (0.57) | GAAPOLBMAPTKDM4ERAB9A | |
| SCHEMBL6719917 | 0.85 | GRIN2D (0.55) | MAPTKDM4EKMT2AMEN1LMNA | |
| SCHEMBL6724060 | 0.84 | CA2 (0.50) | KMT2AMEN1FADS1SIGMAR1GRIN2D | |
| SCHEMBL6720777 | 0.83 | FADS1 (0.45) | GAAKMT2AMEN1LMNAFADS1 | |
| SCHEMBL6719148 | 0.81 | TRPV1 (0.58) | GAAPOLBMAPTKDM4ERAB9A | |
| SCHEMBL6727801 | 0.81 | MAPT (0.52) | POLBMAPTKMT2AMEN1LMNA | |
| SCHEMBL6727618 | 0.81 | GRIN2D (0.40) | GAAPOLBKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL8717419 | 0.80 | GRIN2D (0.39) | GAAPOLBKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190976-A | Neuroprotective | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND UNIVERSITY OF OREGON (US) | 1993-03-02 | — | — | US | disclosed |