Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7341381 | 0.94 | ITGB3 (0.68) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL8044020 | 0.87 | ITGB3 (0.55) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL8688555 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL7345347 | 0.86 | ITGB3 (0.71) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8034450 | 0.86 | ALOX15 (0.56) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL7356492 | 0.85 | F2 (0.52) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL6839445 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8688005 | 0.84 | ALOX15 (0.53) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL27417535 | 0.83 | ITGB3 (0.72) | ITGB3ITGA2BALOX15PRSS1PRSS2 | |
| SCHEMBL7310389 | 0.83 | ITGB3 (0.52) | ITGB3ITGA2BALOX15KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612313-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-31 | — | — | EP | claimed |
| WO-1993010091-A2 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-05-27 | — | — | WO | claimed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | claimed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |