Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085879 | 0.98 | ALDH1A1 (0.53) | ALDH1A1TSHRFDPSHPGDCYP1A2 | |
| SCHEMBL16930085 | 0.89 | ALDH1A1 (0.59) | ALDH1A1TSHRFDPSHPGDCYP1A2 | |
| SCHEMBL2933054 | 0.86 | FDPS (0.54) | ALDH1A1TSHRFDPSHPGDCYP1A2 | |
| SCHEMBL8034223 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TSHRFDPSHPGDMEN1 | |
| SCHEMBL8089378 | 0.84 | FDPS (0.51) | FDPSHTR2AALOX5PTGS2 | |
| SCHEMBL29957052 | 0.83 | ALDH1A1 (0.66) | ALDH1A1TSHRFDPSHPGDCYP1A2 | |
| SCHEMBL2432443 | 0.83 | ALDH1A1 (0.66) | ALDH1A1TSHRFDPSHPGDCYP1A2 | |
| SCHEMBL7420216 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRFDPSHPGDCYP1A2 | |
| SCHEMBL9505345 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRFDPSHPGDCYP1A2 | |
| SCHEMBL5077090 | 0.80 | TSHR (0.46) | ALDH1A1TSHRMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |