Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344641 | 0.84 | ALDH1A1 (0.54) | FDPSHTR2AALOX5PTGS2 | |
| SCHEMBL8085879 | 0.83 | ALDH1A1 (0.53) | FDPSHTR2AALOX5PTGS2PPARA | |
| SCHEMBL9070266 | 0.77 | PPARG (0.55) | HTR2AALOX5PTGS2PPARA | |
| SCHEMBL9889155 | 0.77 | ADRA1A (0.64) | HTR2AALOX5PTGS2ADRA1ATAAR1 | |
| SCHEMBL14122353 | 0.76 | PPARG (0.57) | HTR2AALOX5PTGS2PPARA | |
| SCHEMBL5133668 | 0.76 | ADRA1A (0.62) | HTR2AALOX5PTGS2ADRA1ATAAR1 | |
| SCHEMBL10767997 | 0.76 | ADRA1A (0.62) | HTR2AALOX5PTGS2ADRA1ATAAR1 | |
| SCHEMBL15186292 | 0.76 | HTR2A (0.53) | HTR2AALOX5PTGS2PPARA | |
| SCHEMBL10601156 | 0.76 | ADRA1A (0.62) | HTR2AALOX5PTGS2ADRA1ATAAR1 | |
| SCHEMBL7344634 | 0.75 | HTR2A (0.46) | HTR2AALOX5PTGS2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |