Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17740802 | 0.81 | EPHX1 (0.50) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL2067136 | 0.78 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL29257688 | 0.78 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL3293988 | 0.78 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL1900865 | 0.78 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL1900915 | 0.78 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL646456 | 0.78 | EPHX1 (0.48) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL31021799 | 0.76 | SIGMAR1 (0.41) | EPHX1TP53KDM4EGMNNLMNA | |
| Cyclohexane SCHEMBL2492289 | 0.74 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL21656667 | 0.74 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138259-B2 | Polyamide molding materials with an improved flowability, the production thereof and its use | EMS-CHEMIE AG (CH) | 2012-03-20 | — | — | US | disclosed |
| US-7910652-B2 | Polyamide molding materials with an improved flowability, the production thereof and its use | EMS-CHEMIE AG (CH) | 2011-03-22 | — | — | US | disclosed |
| US-20100028646-A1 | POLYAMIDE MOLDING MATERIALS WITH AN IMPROVED FLOWABILITY, THE PRODUCTION THEREOF AND ITS USE | EMS-CHEMIE AG (CH) | 2010-02-04 | — | — | US | disclosed |
| US-20090131569-A1 | Polyamide Molding Materials with an Improved Flowability, the Production Thereof and Its Use | EMS-CHEMIE AG (CH) | 2009-05-21 | — | — | US | disclosed |