Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344761 | 0.87 | AKR1C3 (0.45) | L3MBTL1MAPTTDP1KDM4EGAA | |
| SCHEMBL155788 | 0.86 | L3MBTL1 (0.56) | L3MBTL1ATMMEN1KMT2AMAPT | |
| SCHEMBL19182818 | 0.86 | L3MBTL1 (0.56) | L3MBTL1ATMMEN1KMT2AMAPT | |
| Formaldehyde SCHEMBL27761906 | 0.83 | L3MBTL1 (0.53) | L3MBTL1ATMMEN1KMT2AMAPT | |
| Methane SCHEMBL7344826 | 0.81 | L3MBTL1 (0.46) | L3MBTL1ATMMEN1KMT2AMAPT | |
| SCHEMBL7345565 | 0.81 | MEN1 (0.45) | L3MBTL1ATMMEN1KMT2AMAPT | |
| SCHEMBL23193598 | 0.77 | ESR1 (0.47) | L3MBTL1MEN1KMT2AMAPTPOLB | |
| Pivalate SCHEMBL8129979 | 0.77 | MEN1 (0.48) | L3MBTL1ATMMEN1KMT2AMAPT | |
| SCHEMBL28465915 | 0.77 | KDM4E (0.46) | L3MBTL1ATMMEN1KMT2ATDP1 | |
| SCHEMBL28465913 | 0.77 | KDM4E (0.46) | L3MBTL1ATMMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663416-A | ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS OR DERMATITIS TREATMENT | CORTECH INC. | 1997-09-02 | — | — | US | disclosed |
| US-5214191-A | OXIDANT SENSITIVE AND INSENSITIVE AROMATIC ESTERS AS INHIBITORS OF HUMAN NEUTROPHIL ELASTASE | CORTECH, INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0465802-A1 | Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase | CORTECH, INC. (US) | 1992-01-15 | — | — | EP | disclosed |
| CN-1056680-A | The preparation method who can be used as the 2-phenylalkanoic acid esters of human leukocytes elastase inhibitor | CORTECH INC (US) | 1991-12-04 | — | — | CN | disclosed |