Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7339460 | 0.94 | ITGB3 (0.63) | ITGB3ITGA2BALOX15UBE2THRH3 | |
| SCHEMBL7346577 | 0.85 | ITGB3 (0.52) | ITGB3ITGA2BALOX15UBE2THRH3 | |
| SCHEMBL7339480 | 0.83 | ITGB3 (0.50) | ITGB3ITGA2BALOX15UBE2THRH3 | |
| SCHEMBL6839445 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2BALOX15 | |
| Trifluoroacetic Acid SCHEMBL7344932 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BALOX15UBE2THRH3 | |
| Hydrochloric Acid SCHEMBL8431411 | 0.81 | ALOX15 (0.98) | ITGB3ITGA2BALOX15 | |
| Hydrochloric Acid SCHEMBL9175583 | 0.81 | UBE2T (0.51) | ITGB3ITGA2BALOX15UBE2THRH3 | |
| SCHEMBL7381654 | 0.80 | UBE2T (0.51) | ITGB3ITGA2BALOX15UBE2TOPRM1 | |
| SCHEMBL19600734 | 0.80 | HRH3 (0.62) | ITGB3ITGA2BALOX15HRH3ADRA1A | |
| SCHEMBL7345723 | 0.80 | ITGB3 (0.49) | ITGB3ITGA2BALOX15HRH3CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612313-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-31 | — | — | EP | claimed |
| CN-1090273-A | Acetogenin | GLAXO GROUP LTD (GB) | 1994-08-03 | — | — | CN | claimed |
| WO-1993010091-A2 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-05-27 | — | — | WO | claimed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | claimed |
| EP-0612313-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993010091-A2 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |
| EP-0542363-A2 | Piperidineacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |