Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136776 | 0.93 | ALDH1A1 (0.38) | TSHRALDH1A1IDO1TP53AGXT | |
| SCHEMBL51153 | 0.89 | TSHR (0.52) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| Hydrochloric Acid SCHEMBL27474797 | 0.87 | TSHR (0.50) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL28006880 | 0.87 | TSHR (0.50) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL15021274 | 0.87 | TSHR (0.50) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL11519078 | 0.82 | TSHR (0.49) | TSHRALDH1A1SLC6A2SLC6A3LMNA | |
| SCHEMBL673603 | 0.82 | TSHR (0.44) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL26947534 | 0.80 | IDO1 (0.45) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL28065470 | 0.79 | LTA4H (0.39) | TSHRALDH1A1IDO1LMNARAB9A | |
| SCHEMBL1450921 | 0.79 | TSHR (0.46) | TSHRALDH1A1IDO1TP53AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916679-B1 | Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-5952327-A | NEUTRAL ENDOPEPTIDASE INHIBITORS; TREATMENT OF CARDIOVASCULAR DISORDERS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1999-09-14 | — | — | US | disclosed |
| CN-1217334-A | Phosphoric-acid substituted benzo-aza-tropone-N-acetic acid derivative, preparing method and medicine thereof | SOLVAY MEDICINES AG (DE) | 1999-05-26 | — | — | CN | disclosed |
| EP-0916679-A1 | Benzazepinone-N-acetic acid derivatives having a phosphonic acid group, process for their preparation and medicaments containing these compounds | Solvay Pharmaceuticals GmbH (DE) | 1999-05-19 | — | — | EP | disclosed |