Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51153 | 0.84 | TSHR (0.52) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL15021274 | 0.82 | TSHR (0.50) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL28006880 | 0.82 | TSHR (0.50) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL27474797 | 0.82 | TSHR (0.50) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL7334884 | 0.80 | TSHR (0.41) | LTA4HALDH1A1TSHRHPGDLMNA | |
| SCHEMBL7344971 | 0.79 | TSHR (0.43) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL28027281 | 0.79 | TSHR (0.36) | ALDH1A1TSHRTACR1LMNAIDO1 | |
| SCHEMBL673603 | 0.77 | TSHR (0.44) | ALDH1A1TSHRHPGDLMNAMAPK1 | |
| SCHEMBL10325280 | 0.76 | SIGMAR1 (0.38) | TSHRKMT2ANPC1RAB9AIDO1 | |
| SCHEMBL26947534 | 0.76 | IDO1 (0.45) | LTA4HALDH1A1TSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752380-B | Water-soluble derivatives and prodrugs of acacetin and methods of making and using same | 港大科桥有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-105566392-A | Bacterial protein synthesis inhibitor preparation method | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |