Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.57 |
| ▸ | CTSL | P07711 | 7/20 | 0.55 |
| ▸ | CTSB | P07858 | 5/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344977 | 1.00 | CTSK (0.57) | CTSKCTSLCTSBCTSSPSMB1 | |
| SCHEMBL7337277 | 0.87 | CTSK (0.59) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7337267 | 0.87 | CTSK (0.59) | CTSKCTSLCTSBCTSS | |
| SCHEMBL25406813 | 0.78 | CTSK (0.77) | CTSKCTSLCTSBCTSS | |
| SCHEMBL2930262 | 0.78 | CTSK (0.77) | CTSKCTSLCTSBCTSS | |
| SCHEMBL14148467 | 0.78 | CTSK (0.77) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4872585 | 0.78 | CTSK (0.77) | CTSKCTSLCTSBCTSS | |
| SCHEMBL8823918 | 0.78 | CTSK (0.77) | CTSKCTSLCTSBCTSS | |
| SCHEMBL20770085 | 0.78 | CTSK (0.77) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7337140 | 0.78 | CTSL (0.53) | CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |