Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 16/20 | 0.55 |
| ▸ | MMP1 | P03956 | 8/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333445 | 0.83 | MMP3 (0.61) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6951176 | 0.78 | MMP3 (0.76) | MMP3MMP1MMP2 | |
| SCHEMBL6951172 | 0.78 | MMP3 (0.76) | MMP3MMP1MMP2 | |
| SCHEMBL6960323 | 0.77 | MMP3 (0.74) | MMP3MMP1MMP2 | |
| SCHEMBL7339581 | 0.76 | MMP3 (0.52) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6950430 | 0.76 | MMP3 (0.76) | MMP3MMP1MMP2 | |
| SCHEMBL7335781 | 0.76 | MMP3 (0.53) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7341498 | 0.76 | CA1 (0.44) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7399055 | 0.74 | MMP3 (0.44) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL8156824 | 0.74 | MMP3 (0.53) | MMP3MMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847148-A | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |