Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 7/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340760 | 0.92 | CACNA1B (0.50) | CACNA1BYAP1PPARG | |
| SCHEMBL7343476 | 0.90 | YAP1 (0.47) | CACNA1BYAP1PPARG | |
| SCHEMBL7347985 | 0.88 | YAP1 (0.50) | CACNA1BYAP1PPARG | |
| SCHEMBL7335997 | 0.86 | PPARG (0.50) | CACNA1BYAP1PPARG | |
| SCHEMBL7348694 | 0.86 | PPARG (0.48) | CACNA1BCYP3A4YAP1PPARG | |
| SCHEMBL7341214 | 0.86 | PPARG (0.47) | YAP1PPARG | |
| SCHEMBL7338702 | 0.86 | PPARG (0.47) | CACNA1BYAP1PPARG | |
| SCHEMBL7339909 | 0.85 | PPARG (0.45) | CACNA1BYAP1PPARG | |
| SCHEMBL7347680 | 0.85 | MEN1 (0.46) | CACNA1BYAP1PPARG | |
| SCHEMBL7346368 | 0.85 | CACNA1B (0.47) | CACNA1BYAP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |