Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337046 | 0.84 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL11141708 | 0.84 | DRD2 (0.56) | RAB9ASMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL30231919 | 0.83 | RAB9A (0.60) | RAB9ASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL8688241 | 0.82 | TSHR (0.50) | RAB9ASMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL11019595 | 0.81 | RAB9A (0.67) | RAB9ASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL28985967 | 0.81 | DRD2 (0.62) | RAB9ASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL30317447 | 0.81 | DRD2 (0.62) | RAB9ASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL212173 | 0.79 | ALDH1A1 (0.79) | RAB9ASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL15923823 | 0.78 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL11224202 | 0.78 | RAB9A (0.59) | RAB9ASMN1; SMN2MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| CN-1192729-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-09-09 | — | — | CN | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |