Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24099161 | 0.90 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL24099262 | 0.88 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL729028 | 0.87 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL3025973 | 0.84 | GSK3B (0.72) | SMN1; SMN2ALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL696173 | 0.84 | GSK3B (0.71) | SMN1; SMN2ALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL10366277 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL1719457 | 0.79 | KMT2A (0.65) | SMN1; SMN2ALDH1A1KMT2AHPGDPOLB | |
| SCHEMBL8562369 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL7344597 | 0.78 | RAB9A (0.55) | SMN1; SMN2HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL7351138 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1HSD17B10KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |