Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351791 | 0.83 | HTT (0.48) | RAB9ANPC1SIGMAR1SMN1; SMN2HTT | |
| SCHEMBL7345361 | 0.78 | SMN1; SMN2 (0.63) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11488668 | 0.76 | RAB9A (0.50) | RAB9ANPC1SIGMAR1SMN1; SMN2HTT | |
| SCHEMBL7353631 | 0.76 | MAPT (0.38) | SMN1; SMN2TSHRHSD17B10DRD2MEN1 | |
| SCHEMBL7352747 | 0.76 | ALDH1A1 (0.43) | RAB9ASIGMAR1TSHRHSD17B10HTR2A | |
| SCHEMBL26584242 | 0.75 | NPC1 (0.82) | RAB9ANPC1SMN1; SMN2HTTHTR7 | |
| SCHEMBL11064187 | 0.75 | NPC1 (0.49) | RAB9ANPC1SIGMAR1SMN1; SMN2HTT | |
| SCHEMBL7350313 | 0.75 | ALDH1A1 (0.68) | SIGMAR1HTTTSHRHSD17B10HTR1A | |
| SCHEMBL11755100 | 0.73 | ALDH1A1 (0.71) | SIGMAR1HTTTSHRHSD17B10HTR1A | |
| Hydrochloric Acid SCHEMBL5360557 | 0.72 | TSHR (0.62) | SIGMAR1TSHRHTR1ADRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |