Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350559 | 0.88 | SLC6A4 (0.40) | KMT2AMEN1SLC6A4ALDH1A1HTR1A | |
| SCHEMBL7350636 | 0.85 | POLB (0.33) | POLBKMT2AMEN1SLC6A4ALDH1A1 | |
| SCHEMBL7352863 | 0.85 | ALDH1A1 (0.48) | POLBKMT2ASLC6A4ALDH1A1MAPT | |
| SCHEMBL7352429 | 0.84 | POLB (0.32) | POLBKMT2AMEN1SLC6A4ALDH1A1 | |
| SCHEMBL7356365 | 0.83 | POLB (0.34) | POLBKMT2AMEN1SLC6A4ALDH1A1 | |
| SCHEMBL7346562 | 0.81 | SLC6A4 (0.49) | SLC6A4HTR1AHTR2AHRH3 | |
| SCHEMBL7356312 | 0.79 | ALDH1A1 (0.41) | POLBKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL7348352 | 0.79 | SLC6A4 (0.44) | SLC6A4ALDH1A1SLC6A9MAPTCYP2D6 | |
| SCHEMBL7347515 | 0.76 | HTR1A (0.43) | SLC6A4HTR1AHTR2AHRH3 | |
| SCHEMBL7348933 | 0.76 | HTR1A (0.42) | SLC6A4HTR1AHTR2ACYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |