Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351114 | 0.86 | L3MBTL1 (0.42) | ALDH1A1HSD17B10POLBPKMTSHR | |
| SCHEMBL7345371 | 0.85 | POLB (0.39) | ALDH1A1POLBKMT2ASLC6A4MAPT | |
| SCHEMBL7349866 | 0.84 | L3MBTL1 (0.41) | ALDH1A1HSD17B10POLBPKMTSHR | |
| SCHEMBL7356394 | 0.83 | L3MBTL1 (0.44) | ALDH1A1HSD17B10POLBPKMTSHR | |
| SCHEMBL14415799 | 0.81 | SLC6A4 (0.52) | ALDH1A1HSD17B10POLBPKMTSHR | |
| SCHEMBL7350559 | 0.81 | SLC6A4 (0.40) | ALDH1A1KMT2ASLC6A4MAPT | |
| SCHEMBL7352732 | 0.80 | RAB9A (0.46) | ALDH1A1HSD17B10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7348352 | 0.78 | SLC6A4 (0.44) | ALDH1A1SLC6A4MAPT | |
| SCHEMBL7346562 | 0.78 | SLC6A4 (0.49) | SLC6A4 | |
| SCHEMBL7347515 | 0.73 | HTR1A (0.43) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |