Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 4/20 | 0.47 |
| ▸ | IL1RN | P18510 | 5/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.46 |
| ▸ | REN | P00797 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345558 | 1.00 | CACNA1B (0.47) | CACNA1BIL1RNERAP2ERAP1REN | |
| SCHEMBL7342868 | 0.91 | CTSL (0.47) | CACNA1BRENCTSSMMP1CTSK | |
| SCHEMBL7338648 | 0.91 | MMP1 (0.53) | CACNA1BRENMMP1PSMB11PSMA7 | |
| SCHEMBL7342865 | 0.91 | CTSL (0.47) | CACNA1BRENCTSSMMP1CTSK | |
| SCHEMBL7338655 | 0.91 | MMP1 (0.53) | CACNA1BRENMMP1PSMB11PSMA7 | |
| SCHEMBL7344934 | 0.89 | CACNA1B (0.58) | CACNA1BIL1RNERAP2ERAP1REN | |
| SCHEMBL7344929 | 0.89 | CACNA1B (0.58) | CACNA1BIL1RNERAP2ERAP1REN | |
| SCHEMBL7342435 | 0.89 | CACNA1B (0.50) | CACNA1BIL1RNERAP2ERAP1REN | |
| SCHEMBL7342880 | 0.89 | CACNA1B (0.58) | CACNA1BIL1RNERAP2ERAP1REN | |
| SCHEMBL21023244 | 0.89 | CACNA1B (0.58) | CACNA1BIL1RNERAP2ERAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |