Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.51 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345612 | 1.00 | CTSS (0.51) | CTSSCTSKALDH1A1HPGDPPARG | |
| SCHEMBL7340544 | 0.91 | ACE (0.54) | CTSSCTSKPPARGPPARAACE | |
| SCHEMBL7340534 | 0.91 | ACE (0.54) | CTSSCTSKPPARGPPARAACE | |
| SCHEMBL7349130 | 0.90 | PPARG (0.52) | CTSSCTSKALDH1A1HPGDPPARG | |
| SCHEMBL7347953 | 0.86 | CTSS (0.55) | CTSSCTSKPPARGPPARAACE | |
| SCHEMBL9181870 | 0.86 | CTSS (0.55) | CTSSCTSKPPARGPPARAACE | |
| SCHEMBL7303351 | 0.84 | REN (0.57) | CTSSCTSKACECTSLCTSB | |
| SCHEMBL7303359 | 0.84 | REN (0.57) | CTSSCTSKACECTSLCTSB | |
| SCHEMBL7340560 | 0.83 | CTSK (0.51) | CTSSCTSKALDH1A1HPGDPPARG | |
| SCHEMBL7340555 | 0.83 | CTSK (0.51) | CTSSCTSKALDH1A1HPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603873-B1 | Aminoketone derivatives | MITSUBISHI CHEM CORP (JP) | 1998-04-15 | — | — | EP | disclosed |
| EP-0603873-A1 | Aminoketone derivatives | Mitsubishi Chemical Corporation (JP) | 1994-06-29 | — | — | EP | disclosed |