Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.66 |
| ▸ | HRH1 | P35367 | 7/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | GHSR | Q92847 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294057 | 0.93 | SIGMAR1 (0.71) | SIGMAR1HRH1ALOX5BRAFHTR2B | |
| SCHEMBL7303340 | 0.81 | SIGMAR1 (0.60) | SIGMAR1HRH1ALOX5BRAFDRD2 | |
| SCHEMBL7299921 | 0.80 | SIGMAR1 (1.00) | SIGMAR1DRD2USP2HTR2BDRD4 | |
| SCHEMBL7302990 | 0.78 | SIGMAR1 (0.68) | SIGMAR1HTR2BMAPK1HTR1ATDP1 | |
| SCHEMBL7305898 | 0.76 | SIGMAR1 (0.77) | SIGMAR1HTR2BLMNAMEN1KMT2A | |
| SCHEMBL3605597 | 0.76 | SIGMAR1 (0.76) | SIGMAR1BRAFDRD2USP2DRD4 | |
| SCHEMBL7294524 | 0.75 | SIGMAR1 (0.76) | SIGMAR1DRD2HTR2BHTR1A | |
| SCHEMBL17237763 | 0.75 | SIGMAR1 (0.75) | SIGMAR1HTR2BLMNAMEN1KMT2A | |
| SCHEMBL7298240 | 0.75 | SIGMAR1 (0.75) | SIGMAR1HTR2BLMNAMEN1KMT2A | |
| SCHEMBL7299989 | 0.75 | SIGMAR1 (0.75) | SIGMAR1HTR2BLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |