Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.36 |
| ▸ | ITGAV | P06756 | 8/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 8/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.36 |
| ▸ | MDM4 | O15151 | 4/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.30 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.30 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPRA | P18433 | 1/20 | 0.30 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344786 | 0.77 | ITGB3 (0.37) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7352151 | 0.69 | ITGB3 (0.44) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7345450 | 0.67 | ITGB3 (0.48) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7355857 | 0.67 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7353534 | 0.66 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL9295158 | 0.66 | ITGB3 (0.43) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7345936 | 0.65 | ITGB3 (0.46) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL9294657 | 0.64 | ITGB3 (0.43) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7346263 | 0.62 | ITGB3 (0.46) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7345928 | 0.62 | PTGER4 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013552-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-20 | — | — | WO | disclosed |