Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.46 |
| ▸ | ITGAV | P06756 | 7/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 7/20 | 0.46 |
| ▸ | MDM4 | O15151 | 4/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353534 | 0.88 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7355857 | 0.83 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7349358 | 0.82 | ITGB3 (0.41) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7355053 | 0.82 | ITGB3 (0.41) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL9294657 | 0.77 | ITGB3 (0.43) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7345450 | 0.75 | ITGB3 (0.48) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7345936 | 0.73 | ITGB3 (0.46) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7352151 | 0.73 | ITGB3 (0.44) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL7345324 | 0.71 | ITGB3 (0.44) | ITGB3ITGB1ITGAVITGA5MDM4 | |
| SCHEMBL27476362 | 0.70 | GPR139 (0.58) | ITGB3ITGB1ITGAVITGA5MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013552-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-20 | — | — | WO | disclosed |