SCHEMBL7345762

SCHEMBL7345762

ON1C=CNc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8333405 0.76 GAA (0.31) GAASMN1; SMN2
SCHEMBL4372136 0.74 BRPF1 (0.36) GAASMN1; SMN2
SCHEMBL1598178 0.74 GAA (0.31) GAASMN1; SMN2
SCHEMBL3120276 0.74 GAA (0.31) GAASMN1; SMN2
SCHEMBL8338720 0.74 GAA (0.32) GAASMN1; SMN2
SCHEMBL5894079 0.72 TLR9 (0.35) GAASMN1; SMN2
SCHEMBL7603127 0.72
SCHEMBL31672881 0.72 GAA (0.38) GAASMN1; SMN2
SCHEMBL7433336 0.72 GAA (0.38) GAASMN1; SMN2
SCHEMBL212380 0.71 LMNA (0.38) GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277850-B1 EFFICIENCY, BIOCOMPATIBILITY, TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS ABBOTT LABORATORIES 2001-08-21 US disclosed
EP-0906306-A1 PYRROLYL QUINOXALINDIONES, THEIR PRODUCTION AND USE AS AMPA RECEPTOR ANTAGONISTS BASF AKTIENGESELLSCHAFT (DE) 1999-04-07 EP disclosed
WO-1997049701-A1 PYRROLYL QUINOXALINDIONES, THEIR PRODUCTION AND USE AS AMPA RECEPTOR ANTAGONISTS BASF AKTIENGESELLSCHAFT (DE) 1997-12-31 WO disclosed