Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345762 | 0.76 | GAA (0.34) | GAASMN1; SMN2 | |
| SCHEMBL3120276 | 0.76 | GAA (0.31) | GAASMN1; SMN2 | |
| SCHEMBL1598178 | 0.76 | GAA (0.31) | GAASMN1; SMN2 | |
| SCHEMBL4372136 | 0.76 | BRPF1 (0.36) | GAASMN1; SMN2 | |
| SCHEMBL7603127 | 0.74 | — | — | |
| SCHEMBL212380 | 0.72 | LMNA (0.38) | GAASMN1; SMN2 | |
| SCHEMBL8335822 | 0.72 | KDM4E (0.36) | GAASMN1; SMN2TLR9 | |
| SCHEMBL29515039 | 0.72 | KDM4E (0.36) | GAASMN1; SMN2TLR9 | |
| SCHEMBL9742171 | 0.71 | GAA (0.40) | GAA | |
| SCHEMBL8338720 | 0.71 | GAA (0.32) | GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107454900-A | Novel imidazo [1,2-A ] quinoxalines and derivatives thereof for the treatment of cancer | 蒙彼利埃大学 | 2017-12-08 | — | — | CN | claimed |
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | claimed |
| CN-102413831-B | Substituted imidazoquinoxalines | BAYER SCHERING PHARMA AG | 2014-06-04 | — | — | CN | claimed |
| CN-102413831-A | Substituted imidazoquinoxalines | BAYER SCHERING PHARMA AG | 2012-04-11 | — | — | CN | claimed |
| CN-100386326-C | 1-hydroxymethyl imidazo [1, 2-a ] quinoxaline compound and application thereof | INST OF TOXIC PHARMACOLOGY ACA (CN) | 2008-05-07 | — | — | CN | claimed |
| CN-1609105-A | 1-hydroxymethyl imidazo [1, 2-alpha ] quinoxaline compound and application thereof | INST OF TOXIC PHARMACOLOGY ACA (CN) | 2005-04-27 | — | — | CN | claimed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| EP-0104445-A2 | Piperidinoquinoxaline derivatives, their preparation and use | BOEHRINGER INGELHEIM KG (DE) | 1984-04-04 | — | — | EP | claimed |
| WO-2025077857-A1 | USE OF PRMT5 INHIBITOR IN TREATMENT OF TUMORS OR CANCERS | 上海湃隆生物科技有限公司 | 2025-04-17 | — | — | WO | disclosed |
| WO-2024067433-A1 | NOVEL PRMT5 INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2024-04-04 | — | — | WO | disclosed |
| CN-107454900-B | Novel imidazo [1,2-A ] quinoxalines and derivatives thereof for the treatment of cancer | 蒙彼利埃大学 | 2020-08-07 | — | — | CN | disclosed |
| EP-3240789-B1 | NEW IMIDAZO[1,2-A]QUINOXALINES AND DERIVATES THEREOF FOR THE TREATMENT OF CANCER | UNIV MONTPELLIER (FR) | 2020-07-29 | — | — | EP | disclosed |
| CN-107454900-A | Novel imidazo [1,2-A ] quinoxalines and derivatives thereof for the treatment of cancer | 蒙彼利埃大学 | 2017-12-08 | — | — | CN | disclosed |
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |
| CN-1609105-A | 1-hydroxymethyl imidazo [1, 2-alpha ] quinoxaline compound and application thereof | INST OF TOXIC PHARMACOLOGY ACA (CN) | 2005-04-27 | — | — | CN | disclosed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| EP-0647137-A4 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF. | UNIV CALIFORNIA WEBER ECKARD (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |
| US-4539323-A | HYPOTENSIVE AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1985-09-03 | — | — | US | disclosed |
| EP-0104445-A2 | Piperidinoquinoxaline derivatives, their preparation and use | BOEHRINGER INGELHEIM KG (DE) | 1984-04-04 | — | — | EP | disclosed |