Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780715 | 0.94 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTHTTHPGD | |
| SCHEMBL7778674 | 0.86 | KMT2A (0.42) | ALDH1A1LMNAMAPTHTTHPGD | |
| SCHEMBL7340123 | 0.85 | KMT2A (0.36) | ALDH1A1LMNAMAPTHTTHPGD | |
| SCHEMBL7339161 | 0.85 | CDK1 (0.35) | LMNAMAPTHTTCDK1CDK4 | |
| SCHEMBL7340129 | 0.85 | KMT2A (0.36) | ALDH1A1LMNAMAPTHTTHPGD | |
| SCHEMBL7340721 | 0.83 | AVPR2 (0.39) | ALDH1A1LMNAMAPTHTTHPGD | |
| SCHEMBL7345832 | 0.82 | AVPR2 (0.46) | ALDH1A1LMNAMEN1KMT2AAVPR2 | |
| SCHEMBL7337098 | 0.81 | CDK1 (0.36) | CDK1CDK4CCND1CDK2ACHE | |
| SCHEMBL7340552 | 0.80 | CDK1 (0.36) | LMNAMAPTHTTCDK1CDK4 | |
| SCHEMBL7478475 | 0.79 | CBX7 (0.38) | ALDH1A1MAPTHPGDMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |