Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346340 | 0.79 | TMEM97 (0.48) | HTR3A | |
| SCHEMBL7346437 | 0.75 | HTR3E (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7346433 | 0.75 | HTR3E (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10913532 | 0.74 | ALOX15 (0.55) | LMNACYP2D6CYP2C9HSD17B10HTR3E | |
| SCHEMBL7347059 | 0.71 | CHRM2 (0.38) | CHRM2CHRM1CHRM3CHRM4SMN1; SMN2 | |
| SCHEMBL10917860 | 0.71 | ALOX15 (0.52) | LMNACYP2D6CYP2C9HSD17B10HTR3E | |
| SCHEMBL7386968 | 0.71 | HTR3E (0.55) | LMNACYP2D6CYP2C9HSD17B10HTR3E | |
| SCHEMBL21912571 | 0.71 | BCHE (0.52) | LMNAHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL9602046 | 0.70 | ALOX15 (0.58) | LMNACYP2D6CYP2C9HSD17B10HTR3E | |
| SCHEMBL25180710 | 0.69 | HSD17B10 (0.45) | LMNAHSD17B10KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399562-A | 5-hydroxytryptamine agonists or antagonists; gastrointestinal disorders | G. D. SEARLE & CO. (US) | 1995-03-21 | — | — | US | disclosed |