Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346433 | 0.95 | HTR3E (0.44) | TMEM97SIGMAR1HTR3A | |
| SCHEMBL7346437 | 0.95 | HTR3E (0.44) | TMEM97SIGMAR1HTR3A | |
| SCHEMBL7352208 | 0.87 | TMEM97 (0.47) | TMEM97SIGMAR1HTR3AHTR4 | |
| SCHEMBL7347059 | 0.82 | CHRM2 (0.38) | — | |
| Ricasetron SCHEMBL20362251 | 0.80 | NOTUM (0.52) | TMEM97SIGMAR1HTR3AHTR4 | |
| Ricasetron SCHEMBL634826 | 0.80 | NOTUM (0.52) | TMEM97SIGMAR1HTR3AHTR4 | |
| Ricasetron SCHEMBL21715163 | 0.80 | NOTUM (0.52) | TMEM97SIGMAR1HTR3AHTR4 | |
| Ricasetron SCHEMBL634827 | 0.80 | NOTUM (0.52) | TMEM97SIGMAR1HTR3AHTR4 | |
| SCHEMBL7346200 | 0.79 | LMNA (0.50) | HTR3A | |
| Ricasetron SCHEMBL7445859 | 0.79 | NOTUM (0.51) | TMEM97SIGMAR1HTR3AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399562-A | 5-hydroxytryptamine agonists or antagonists; gastrointestinal disorders | G. D. SEARLE & CO. (US) | 1995-03-21 | — | — | US | claimed |
| US-5399562-A | 5-hydroxytryptamine agonists or antagonists; gastrointestinal disorders | G. D. SEARLE & CO. (US) | 1995-03-21 | — | — | US | disclosed |