Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | SCN1A | P35498 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344814 | 0.94 | HSD17B10 (0.57) | HSD17B10MAPTADORA3CYP1A2KMT2A | |
| SCHEMBL7347242 | 0.91 | ADORA3 (0.69) | HSD17B10MAPTADORA3CYP1A2KMT2A | |
| SCHEMBL9674378 | 0.85 | ADORA3 (0.66) | HSD17B10MAPTADORA3CYP1A2KMT2A | |
| SCHEMBL9672675 | 0.85 | ADORA3 (0.65) | HSD17B10MAPTADORA3CYP1A2KMT2A | |
| SCHEMBL7350843 | 0.85 | MAPT (0.70) | MAPTADORA3CYP1A2KMT2AHIF1A | |
| SCHEMBL10918103 | 0.85 | MAPT (0.70) | MAPTADORA3CYP1A2KMT2AHIF1A | |
| SCHEMBL7350016 | 0.84 | HSD17B10 (0.56) | HSD17B10MAPTADORA3CYP1A2KMT2A | |
| SCHEMBL9674762 | 0.84 | ADORA3 (0.64) | HSD17B10MAPTADORA3CYP1A2KMT2A | |
| SCHEMBL7346357 | 0.83 | CYP1A2 (0.54) | HSD17B10MAPTADORA3CYP1A2KMT2A | |
| SCHEMBL7341132 | 0.83 | HSD17B10 (0.59) | HSD17B10MAPTADORA3CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833150-A | HYPOTENSIVES, ANTIARRHYTHMIA AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4652573-A | HYPOTENSIVE AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0194685-A1 | 1,4-Dihydropyridines | Whitby Research Incorporated (US) | 1986-09-17 | — | — | EP | disclosed |