Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908567 | 0.84 | LMNA (0.59) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12970697 | 0.83 | LMNA (0.57) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10473353 | 0.80 | MEN1 (0.54) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL220681 | 0.80 | NPC1 (0.64) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL17202768 | 0.78 | MEN1 (0.59) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10473282 | 0.77 | MEN1 (0.51) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3291689 | 0.77 | TSHR (0.50) | LMNAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11756782 | 0.77 | ACHE (0.52) | LMNAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL1423874 | 0.77 | FLT1 (0.55) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27680097 | 0.77 | AVPR2 (0.46) | MEN1KMT2ACYP3A4TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207327-A | N-(4-Pyrazolidinyl)benzamides and their amino precursors | A. H. ROBINS COMPANY, INC. (US) | 1980-06-10 | — | — | US | disclosed |