Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | NOS2 | P35228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346888 | 0.90 | NPC1 (0.40) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL7344633 | 0.85 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL7353137 | 0.83 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL7346830 | 0.82 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7348352 | 0.81 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL7356365 | 0.80 | POLB (0.34) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7346191 | 0.80 | CALM1 (0.36) | SLC6A4IDO1 | |
| SCHEMBL7356394 | 0.80 | L3MBTL1 (0.44) | — | |
| SCHEMBL7346492 | 0.80 | SLC6A4 (0.42) | SLC6A4 | |
| SCHEMBL7348954 | 0.78 | SLC6A4 (0.32) | SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |