Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351073 | 0.84 | HDAC3 (0.44) | MEN1KMT2AMAPK1HDAC3HDAC1 | |
| SCHEMBL7352468 | 0.82 | HTT (0.44) | MEN1KMT2AMAPK1HDAC3HDAC1 | |
| SCHEMBL13083453 | 0.80 | KDM4E (0.49) | MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL7346155 | 0.77 | L3MBTL1 (0.56) | MEN1KMT2AMAPK1HDAC3HDAC1 | |
| SCHEMBL7345960 | 0.76 | TMEM97 (0.54) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL7346214 | 0.76 | KDM4E (0.50) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL8725187 | 0.72 | KMT2A (0.59) | MEN1KMT2AMAPK1HDAC3HDAC1 | |
| SCHEMBL7344617 | 0.71 | HTT (0.44) | MEN1KMT2AMAPK1HTTMEP1B | |
| SCHEMBL6847922 | 0.70 | L3MBTL1 (0.65) | MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL5146175 | 0.69 | HDAC3 (0.62) | MAPK1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |